Post-transfusion purpura: a heterogeneous syndrome
نویسندگان
چکیده
منابع مشابه
Post-transfusion purpura: a heterogeneous syndrome.
Three new patients with post-transfusion purpura (PTP) are described. As the manifestations in two differ significantly from those of previously reported cases, they serve to expand the definition of this syndrome. Although all 14 previously reported cases have occurred in Pl-A1-negative females, one of our patients was a Pl-A-negative male. Moreover, a female whose postrecovery platelets posse...
متن کاملPost-transfusion purpura.
Post-transfusion purpura is a complication of blood product transfusion in which the recipient produces antiplatelet antibodies resulting in severe thrombocytopenia. The typical patient is a multiparous woman who develops sudden severe purpura 1 week after receiving a transfusion of packed red cells or whole blood. Post-transfusion purpura should, however, be considered in any patient with thro...
متن کاملPost-transfusion purpura: a challenging diagnosis.
BACKGROUND Post-transfusion purpura is a rare syndrome characterized by severe thrombocytopenia and bleeding caused by alloimunization to human platelet specific antigens following a blood component transfusion. The suggested incidence is 1:50,000-100,000 transfusions, most often occurring in multiparous women. The diagnosis is not easy because these patients, who are often critically ill or po...
متن کاملPost transfusion purpura in a thalassemic child.
Post transfusion purpura (PTP) is a rare condition and only 200 cases have been reported so far. It is commonly seen in women, with a preponderance in the sixth and seventh decade. Majority of these cases have been observed in whites and the condition is rare among Asian patients(l). It has not yet been reported in children(2). PTP is characterized by the development of thrombocytopenia associa...
متن کاملIsoantibody specificity in post-transfusion purpura.
Pl’ ’-positive platelets that fixed complement with the reference anti PlAl did not fix comp!ement with this patient’s antibody. When used with these platelets, the patient’s antibody competitively blocked the complement-fixing activity of reference anti PlAl. There was no evidence for lack of antigenic sites on the noncomplementfixing platelets or for antibodies with more than one specificity ...
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ژورنال
عنوان ژورنال: Blood
سال: 1975
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v45.4.529.529